KLRG1 Antikörper

Produktnummer ABIN7670189

Dieser Anti-KLRG1-Antikörper ist ein Golden Syrian Hamster-Monoklonal-Antikörper zum Nachweis von KLRG1 in FACS. Geeignet für Human und Maus.

Kurzübersicht für KLRG1 Antikörper (ABIN7670189)

Target: KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))

Reaktivität: Human, Maus

Wirt: Golden Syrian Hamster

Klonalität: Monoklonal

Konjugat: Dieser KLRG1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 2F1

Produktdetails anti-KLRG1 Antikörper

Verwendungszweck: AF/LE Purified Anti-Human/Mouse KLRG-1 Antibody[2F1]

Endotoxin-Niveau: Low Endotoxin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: ≥ 1 mg/mL

Buffer: Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.

Konservierungsmittel: Azide free

Handhabung: avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Haltbarkeit: 12 months

Details zu KLRG1

Target: KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))

Andere Bezeichnung: KLRG-1

Hintergrund: MAFA, 2F1-Ag,Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag).? KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3.? It is composed of a homodimer of glycosylated 30-38 kD subunits.? Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells.? KLRG1 is also expressed on subsets of CD8+?and CD4+?cells, including CD4+?and CD8+?effector/memory cells, potent regulatory CD4+?T cells.? KLRG1 may be involved in regulating NK cell homeostasis.? KLRG2 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.

UniProt: Q96E93, O88713