Interleukin 17a Antikörper

Produktnummer ABIN7670182

Der Maus Monoklonal anti-Interleukin 17a Antikörper wird verwendet zum Nachweis von Interleukin 17a in Proben von Maus. Er wurde validiert für ICFC.

Kurzübersicht für Interleukin 17a Antikörper (ABIN7670182)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Interleukin 17a Antikörper ist unkonjugiert

Applikation: Intracellular Flow Cytometry (ICFC)

Klon: 17F3

Produktdetails anti-Interleukin 17a Antikörper

Verwendungszweck: AF/LE Purified Anti-Mouse IL-17A Antibody[17F3]

Endotoxin-Niveau: Low Endotoxin

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: ≥ 1 mg/mL

Buffer: Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.

Konservierungsmittel: Azide free

Handhabung: avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Haltbarkeit: 12 months

Details zu Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Andere Bezeichnung: IL-17A

Hintergrund: Interleukin-17A,Il17a,Ctla9,The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-18A?in vivo.

UniProt: Q62386