CD1d Antikörper
Kurzübersicht für CD1d Antikörper (ABIN7670151)
Target
Alle CD1d (CD1D) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- AF/LE Purified Anti-Mouse CD1d Antibody[1B1]
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Endotoxin-Niveau
- Low Endotoxin
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- ≥ 1 mg/mL
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Buffer
- Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.
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Konservierungsmittel
- Azide free
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Handhabung
- avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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Haltbarkeit
- 12 months
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- CD1d (CD1D) (CD1d Molecule (CD1D))
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Andere Bezeichnung
- CD1d
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Hintergrund
- Antigen-presenting glycoprotein CD1d1,Cd1d1,CD1d.1,Cd1d1,Cd1.1,CD1d, known as CD1.1 and Ly-38, is a 48 kD type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. In humans, CD1 family consists of group I proteins (CD1a, CD1b, and CD1c), group II (CD1d), and group III (CD1e). But CD1d is the only CD1 Molecule has been found in mouse. Mouse CD1d has broad tissue distribution, and is found on leukocytes, dendritic cells, epithelial cells, and thymocytes. CD1d plays a role in non-peptide glycolipid antigen presentation to CD1d-restricted T cells. It has been shown that PKCδ is a critical regulator of CD1d-mediated antigen presentation.
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UniProt
- P11609
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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