MCAM Antikörper

Produktnummer ABIN7670102

Dieses Anti-MCAM-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von MCAM in FACS. Geeignet für Human.

Kurzübersicht für MCAM Antikörper (ABIN7670102)

Target: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MCAM Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: AA98

Produktdetails anti-MCAM Antikörper

Verwendungszweck: Purified Anti-Human CD146 Antibody[AA98]

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze / thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu MCAM

Target: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Andere Bezeichnung: CD146

Hintergrund: MUC,cell surface glycoprotein MUC,MCAM,CD146,MUC18,cell surface glycoprotein MUC18, S-endo, MCAM, Mel-CAM, Endo-CAM,CD146,cell surface glycoprotein MUC18,MUC18,A32 antigen,CD 146,CD146 antigen,Cell surface glycoprotein P1H12,Gicerin,Melanoma adhesion molecule,Melanoma associated antigen A32,Melanoma associated antigen MUC18,Melanoma associated glycoprotein MUC18,melanoma cell adhesion molecule,Melanoma-associated antigen A32,Melanoma-associated antigen MUC18,MelCAM,MUC 18,S endo 1,S endo 1 endothelial associated antigen,S-endo 1 endothelial-associated antigen,Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

UniProt: P43121