Sca-1/Ly-6A/E Antikörper

Produktnummer ABIN7670100

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch Sca-1/Ly-6A/E in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Sca-1/Ly-6A/E Antikörper (ABIN7670100)

Target: Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Sca-1/Ly-6A/E Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: D7

Produktdetails anti-Sca-1/Ly-6A/E Antikörper

Verwendungszweck: Purified Anti-Mouse Ly6A/E Antibody[D7]

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze / thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu Sca-1/Ly-6A/E

Target: Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

Andere Bezeichnung: Ly6A/E

Hintergrund: SCA,Ly-6A2/Ly-6E,Ly-6A.2/Ly-6E.1,SCA-1,TAP,Ly6,Ly6a,Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

UniProt: P05533

Pathways: Sensory Perception of Sound, Activated T Cell Proliferation