This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
avoid freeze / thaw cycles.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Haltbarkeit
12 months
Target
CCR4
(Chemokine (C-C Motif) Receptor 4 (CCR4))
Andere Bezeichnung
CD194
Hintergrund
CCR,CKR,MGC,HGCN,CMKBR,ChemR,CC-CKR,CC-CKR-4,ChemR13,CKR4,HGCN:14099,K5-5,MGC88293,CMKBR4,CCR4,C-C motif chemokine receptor 4,CD194,High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.