CD163 Antikörper

Produktnummer ABIN7669986

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD163 in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD163 Antikörper (ABIN7669986)

Target: CD163

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD163 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: GHI-61

Produktdetails anti-CD163 Antikörper

Verwendungszweck: Purified Anti-Human CD163 Antibody[GHI/61]

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze / thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu CD163

Target: CD163

Andere Bezeichnung: CD163

Hintergrund: GHI/,SCARI,CD163,M130,MM130,SCARI1,ED2(rat),GHI/61,Hemoglobin/Haptoglobin Complex Receptor,macrophage-associated antigen,p155,RM3/1, GHI/61,The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

UniProt: Q86VB7