WT1 Antikörper (Biotin)

Produktnummer ABIN7662050

Der Kaninchen Polyklonal Anti-WT1-Antikörper wurde für IHC und IHC (fp) validiert. Er ist geeignet, WT1 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für WT1 Antikörper (Biotin) (ABIN7662050)

Target: WT1 (Wilms Tumor 1 (WT1))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WT1 Antikörper ist konjugiert mit Biotin

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-WT1 Antikörper (Biotin)

Verwendungszweck: Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker), Biotin conjugate

Produktmerkmale: Recognizes a 47-55 kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human WT1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: K562 cells. Wilm's Tumor, mesothelioma or fetal kidney.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu WT1

Target: WT1 (Wilms Tumor 1 (WT1))

Andere Bezeichnung: Wilms Tumor 1

Hintergrund:

Synonyms: WT1, AWT1, FWT1, GUD, NPHS4, WAGR, Wilms tumor 1

Gene Symbol: WT1

Molekulargewicht: 47-55 kDa

Gen-ID: 7490

UniProt: P19544

Pathways: Tube Formation