Uroplakin 3A Antikörper (AA 260-279) (CF®740)

Produktnummer ABIN7661693

Der Kaninchen Polyklonal Anti-Uroplakin 3A-Antikörper wurde für WB validiert. Er ist geeignet, Uroplakin 3A in Proben von Human zu detektieren.

Kurzübersicht für Uroplakin 3A Antikörper (AA 260-279) (CF®740) (ABIN7661693)

Target: Uroplakin 3A (UPK3A)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Uroplakin 3A Antikörper ist konjugiert mit CF®740

Applikation: Western Blotting (WB)

Produktdetails anti-Uroplakin 3A Antikörper (CF®740)

Bindungsspezifität: AA 260-279

Verwendungszweck: UPK3A (Uroplakin 3A)(Rabbit PAb), CF740 conjugate

Produktmerkmale: Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 1-2 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Western blotting 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user

Kommentare:

Positive Control: HEK293 cells or bladder carcinoma

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu Uroplakin 3A

Target: Uroplakin 3A (UPK3A)

Andere Bezeichnung: UPK3A

Hintergrund:

Synonyms: UP3a, UPIIIA, UPK3A, Uroplakin III (UPIII), Uroplakin3A

Gene Symbol: UPK3A

Tissue Expression: Urothelial cells

Molekulargewicht: ~30 kDa

Gen-ID: 7380

UniProt: O75631