TACSTD2 Antikörper (AA 31-274) (CF®594)

Produktnummer ABIN7661448

Dieses Anti-TACSTD2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von TACSTD2 in WB, IHC und IHC (fp). Geeignet für Human.

Kurzübersicht für TACSTD2 Antikörper (AA 31-274) (CF®594) (ABIN7661448)

Target: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TACSTD2 Antikörper ist konjugiert mit CF®594

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: TACSTD2-2151

Produktdetails anti-TACSTD2 Antikörper (CF®594)

Bindungsspezifität: AA 31-274

Verwendungszweck: TACSTD2 / TROP2 (Epithelial Marker) (TACSTD2/2151), CF594 conjugate

Produktmerkmale: TACSTD2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment of human TACSTD2 protein (around aa 31-274)

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 1-2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Western blotting 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user

Kommentare:

Positive Control: HT29 cells. Breast or Colon Carcinoma

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu TACSTD2

Target: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Andere Bezeichnung: TACSTD2

Hintergrund:

Synonyms: Cell surface glycoprotein Trop-2, Membrane Component Chromosome 1, Surface Marker 1 (M1S1), Pancreatic Carcinoma Marker Protein GA733-1, TROP2, Tumor-Associated Calcium Signal Transducer 2 (TACSTD2)

Gene Symbol: TACSTD2

Tissue Expression: Cornea|Epithelial cells|Placenta

Molekulargewicht: 40 kDa

Gen-ID: 4070

UniProt: P09758