TTR Antikörper (CF®568)

Produktnummer ABIN7661065

Dieses Maus Monoklonal-Antikörper erkennt spezifisch TTR in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TTR Antikörper (CF®568) (ABIN7661065)

Target: TTR (Transthyretin (TTR))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TTR Antikörper ist konjugiert mit CF®568

Applikation: Western Blotting (WB)

Klon: CPTC-TTR-1

Produktdetails anti-TTR Antikörper (CF®568)

Verwendungszweck: Transthyretin (Prealbumin)(CPTC-TTR-1), CF568 conjugate

Produktmerkmale: Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermediate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human full-length protein

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: ELISA: For coating, order Ab without BSA, Western blot 1-2 μg/mL, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody

Kommentare:

Positive Control: HepG2, Pancreas and liver.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu TTR

Target: TTR (Transthyretin (TTR))

Andere Bezeichnung: Transthyretin

Hintergrund:

Synonyms: Transthyretin, PALB, HsT2651, prealbumin, amyloidosis type 1, ATTR, TBPA, CTS, CTS1, carpal tunnel syndrome 1, thyroxine-binding prealbumin, prealbumin, HEL111, TTR protein, Epididymis luminal protein 111, prealbumin thyroxine binding, senile systemic amyloidosis antibody

Gene Symbol: TTR

Molekulargewicht: 15 kDa

Gen-ID: 7276

UniProt: P02766

Pathways: Hormone Transport