TGF-beta Antikörper (CF®488A)

Produktnummer ABIN7660692

Dieses Anti-TGF-beta-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von TGF-beta in . Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Hamster und Affe.

Kurzübersicht für TGF-beta Antikörper (CF®488A) (ABIN7660692)

Target: TGF-beta (TGFb)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Hamster, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TGF-beta Antikörper ist konjugiert mit CF®488A

Applikation: Bitte anfragen

Klon: TGFB-510

Produktdetails anti-TGF-beta Antikörper (CF®488A)

Verwendungszweck: TGF-beta (Transforming Growth Factor beta)(TGFB/510), CF488A conjugate

Produktmerkmale: This MAb recognizes TGF beta 1, 2 and 3. TGFs inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells. Most breast lesions, benign and malignant, involve abnormal proliferation and altered architecture of stromal and/or epithelial elements.

Immunogen: Full length recombinant human TGF-beta2 protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Kommentare:

Positive Control: Ovarian carcinoma, lung tumor or skin. PC-3 cell line. Eahy926 cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu TGF-beta

Target: TGF-beta (TGFb)

Andere Bezeichnung: TGF-Beta

Hintergrund:

Synonyms: ARVD, BSC 1 cell growth inhibitor, CED, Cetermin, Diaphyseal dysplasia 1 (DPD1), Glioblastoma derived T cell suppressor factor (G TSF), Latency-associated peptide (LAP), Polyergin, Transforming growth factor beta 1 (TGF beta1 or TGFB1), TGF beta2 (TGFB2), TGF beta3 (TGFB3), TGFbeta (TGFB)

Gene Symbol: TFGB

Molekulargewicht: ~13 kDa

Gen-ID: 7040, 7042, 7043

UniProt: P01137, P10600, P61812

Pathways: EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus