Rekombinanter SOX9 Antikörper (CF®740)

Produktnummer ABIN7660352

Der Kaninchen Monoklonal Anti-SOX9-Antikörper wurde für validiert. Er ist geeignet, SOX9 in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter SOX9 Antikörper (CF®740) (ABIN7660352)

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser SOX9 Antikörper ist konjugiert mit CF®740

Applikation: Bitte anfragen

Klon: SOX9-2287R

Produktdetails anti-SOX9 Antikörper (CF®740)

Verwendungszweck: SOX9 / SRY-box 9(SOX9/2287R), CF740 conjugate

Produktmerkmale: The specificity of this monoclonal antibody to its intended target was validated by HuProt™, Array, containing more than 19, 000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) : Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human full-length SOX9 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Kommentare:

Positive Control: Human Skin Hair follicles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu SOX9

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Andere Bezeichnung: SOX9

Hintergrund:

Synonyms: CMD 1, campomelic dysplasia autosomal sex reversal, SRA1, SRXX2, SRXY10, SRY (sex determining region Y) box 9, SRY related HMG box gene 9, Transcription factor SOX 9

Gene Symbol: SOX9

Molekulargewicht: 56 kDa

Gen-ID: 6662

UniProt: P48436

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development