Rekombinanter s100a4 Antikörper (AA 1-200) (CF®640R)
Kurzübersicht für Rekombinanter s100a4 Antikörper (AA 1-200) (CF®640R) (ABIN7659699)
Target
Alle s100a4 (S100A4) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 1-200
-
Verwendungszweck
- S100A4 / Metastasin / Calvasculin (Marker of Tumor Metastasis)(rS100A4/1481), CF640R conjugate
-
Produktmerkmale
- S100A4 belongs to the S100 super-family of proteins containing 2 EF-hand calcium-binding domains. S100 genes include at least 25 members, including S100A1-S100A18, trichohyalin, filaggrin, repetin, S100P, and S100Z. S100A4 exerts its function via direct interaction with a number of proteins including P53, P63, non-muscle myosin IIA, 64 integrin, and liprin b1. S100A4 is overexpressed in highly metastatic cancers, which makes it useful as a marker of tumor progression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
-
Immunogen
- Recombinant fragment (around aa 1-200) of human S100A4 protein
-
Isotyp
- IgG1, kappa
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Kommentare
-
Positive Control: HeLa, A549 or A375 cells (IF/FACS). HeLa, A549, T98G or A375 cell lysate (WB). Human placenta tissue (IHC).
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.1 mg/mL
-
Buffer
- PBS, 0.1 % BSA, 0.05 % azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Protect from light
-
Lagerung
- 4 °C
-
Informationen zur Lagerung
-
Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
-
Haltbarkeit
- 24 months
-
-
- s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
-
Andere Bezeichnung
- Calvasculin
-
Hintergrund
-
Synonyms: S100 calcium-binding protein A4, CAPL, Fibroblast specific protein 1 (FSP1), Leukemia multidrug resistance associated protein, Malignant transformation suppression 1 (MTS1), Metastasin, Placental calcium-binding protein
Gene Symbol: S100A4
-
Molekulargewicht
- 10-12 kDa
-
Gen-ID
- 6275
-
UniProt
- P26447
-
Pathways
- S100 Proteine
Target
-