NKX2-8 Antikörper (AA 10-123)

Produktnummer ABIN7657993

Dieses Maus Monoklonal-Antikörper erkennt spezifisch NKX2-8 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für NKX2-8 Antikörper (AA 10-123) (ABIN7657993)

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NKX2-8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: NKX28-2548

Produktdetails anti-NKX2-8 Antikörper

Bindungsspezifität: AA 10-123

Verwendungszweck: NKX2.8(NKX28/2548)

Produktmerkmale: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Human recombinant NKX2.8 protein fragment (around aa 10-123)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: ELISA: For coating, order antibody without BSA, Flow cytometry: 1-2 μg/million cells, Western blot 0.5-1 μg/mL, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody

Kommentare:

Positive Control: Human Liver, Kidney or Thyroid tissue (IHC).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS, 0.05 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu NKX2-8

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Andere Bezeichnung: NKX2.8

Hintergrund:

Synonyms: Homeobox protein NK 2 homolog H, Homeobox protein NK-2 homolog H, Homeobox protein Nkx 2.8, Homeobox protein Nkx-2.8, NK 2 homolog 8, NK 2 homolog H, NK2 homeobox 8, NK2 transcription factor related, locus 8, Nkx2 9, Nkx2-8, NKX2.8, NKX28_HUMAN, NKX2G, NKX2H, OTTHUMP00000027959

Gene Symbol: NKX2-8

Molekulargewicht: 26 kDa

Gen-ID: 26257

UniProt: O15522