Rekombinanter MYH11 Antikörper (CF®405S)

Produktnummer ABIN7657672

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch MYH11 in IHC und IHC (fp). Er zeigt eine Reaktivität gegenüber Human, Ratte, Cat, Huhn, Rind (Kuh), Hund, Meerschweinchen, Schwein und Kaninchen.

Kurzübersicht für Rekombinanter MYH11 Antikörper (CF®405S) (ABIN7657672)

Target: MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Ratte, Cat, Huhn, Rind (Kuh), Hund, Meerschweinchen, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MYH11 Antikörper ist konjugiert mit CF®405S

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: MYH11-2303R

Produktdetails anti-MYH11 Antikörper (CF®405S)

Verwendungszweck: Smooth Muscle Myosin Heavy Chain (SM-MHC) (MYH11/2303R), CF405S conjugate

Produktmerkmale: Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human MYH11 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 0.5-1 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user

Kommentare:

Positive Control: Uterus or normal breast

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu MYH11

Target: MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

Andere Bezeichnung: Smooth Muscle Myosin Heavy Chain

Hintergrund:

Synonyms: AAT4, Myosin heavy chain 11 (MYH11), Myosin heavy chain 11 smooth muscle, Smooth muscle myosin heavy chain 11, Myosin-11, SM1, SM2, SMHC, SMMHC

Gene Symbol: MYH11

Tissue Expression: Smooth muscle

Molekulargewicht: 205 kDa (MHC-1) and 200 kDa (MHC-2)

Gen-ID: 4629

UniProt: P35749