Rekombinanter Myoglobin Antikörper (CF®740)
Kurzübersicht für Rekombinanter Myoglobin Antikörper (CF®740) (ABIN7657657)
Target
Alle Myoglobin (MB) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Myoglobin (Muscle Cell Marker)(rMB/2105), CF740 conjugate
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Produktmerkmale
- Myoglobin is a cytosolic oxygen-binding protein responsible for the storage and diffusion of oxygen within myocytes. Expression of myoglobin is highest in skeletal and cardiac muscle. Myoglobin is well accepted as an O2-storage protein in muscle, capable of releasing O2 during periods of hypoxia or anoxia. In combination with other striated muscle markers such as vimentin and myogenin, myoglobin is helpful in the identification of rhabdomyosarcoma and tumors with skeletal muscle differentiation. Reportedly, myoglobin is expressed on epithelial cancer cells due to changed metabolic and environmental conditions. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogen
- Recombinant human full-length Myoglobin (MB) protein.
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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Positive Control: SK-BR3 or T47D cells. Skeletal or Cardiac Muscle.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % rBSA, 0.05 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Protect from light
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Lagerung
- 4 °C
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Informationen zur Lagerung
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Haltbarkeit
- 24 months
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- Myoglobin (MB)
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Andere Bezeichnung
- Myoglobin
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Hintergrund
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Synonyms: MB, Myoglobin, PVALB
Gene Symbol: MB
Tissue Expression: Muscle
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Molekulargewicht
- 17 kDa
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Gen-ID
- 4151
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UniProt
- P02144
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Pathways
- Brown Fat Cell Differentiation
Target
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