Moesin Antikörper

Produktnummer ABIN7657234

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Moesin in WB, IHC, IF, FACS und IHC (fp). Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für Moesin Antikörper (ABIN7657234)

Target: Moesin (MSN)

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Moesin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: MSN-491

Produktdetails anti-Moesin Antikörper

Verwendungszweck: Moesin(MSN/491)

Produktmerkmale: Recognizes 78 kDa moesin protein. Moesin, a member of the talin-4. 1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human Moesin protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: K562, HT-29, CH3LC or HUVEC cells. Uterus, Placenta, Tonsil, Melanoma, Testicular Carcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS, 0.05 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu Moesin

Target: Moesin (MSN)

Andere Bezeichnung: Moesin

Hintergrund:

Synonyms: Membrane-organizing extension spike protein, Moesin/anaplastic lymphoma kinase fusion protein, MSLK fusion

Gene Symbol: MSN

Molekulargewicht: 78 kDa

Gen-ID: 4478

UniProt: P26038

Pathways: Asymmetric Protein Localization