MHC, Class I Antikörper (CF®740)

Produktnummer ABIN7657101

Dieses Anti-MHC, Class I-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von MHC, Class I in IF. Geeignet für Maus, Human und Non-Human Primate.

Kurzübersicht für MHC, Class I Antikörper (CF®740) (ABIN7657101)

Target: MHC, Class I

Reaktivität: Maus, Human, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MHC, Class I Antikörper ist konjugiert mit CF®740

Applikation: Immunofluorescence (IF)

Klon: 246-B8-E7

Produktdetails anti-MHC, Class I Antikörper (CF®740)

Verwendungszweck: MHC I(246-B8.E7), CF740 conjugate

Produktmerkmale: Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Human peripheral blood leukocytes

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Optimal dilution for a specific application should be determined by user

Kommentare:

Positive Control: THP-1 and Jurkat cells. Tonsil or lymph node.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu MHC, Class I

Target: MHC, Class I

Andere Bezeichnung: MHC-I

Hintergrund:

Synonyms: HLA-A, HLA-B, HLA-C, HLA class 1A, HLA class 1B, HLA class 1C, Major histocompatibility complex, class I, A B C, MHC class I HLA-A, MHC class I HLA-B, MHC class I HLA-C, MHC HLA-ABC

Gene Symbol: HLA-A

Molekulargewicht: ~41 kDa

Gen-ID: 3105

UniProt: P01889, P30443, P30499