CD57 Antikörper (AA 21-120)

Produktnummer ABIN732308

Für dieses Produkt sind 2+ Publikationen verfügbar. Der Kaninchen-Polyklonal Anti-CD57-Antikörper wurde für FACS, WB, IHC (p), ELISA, IF (cc), IF (p) und IHC (fro) validiert. Er ist geeignet zum Nachweis von CD57 in Proben aus Human, Maus und Ratte. }

Kurzübersicht für CD57 Antikörper (AA 21-120) (ABIN732308)

Target: CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD57 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-CD57 Antikörper

Bindungsspezifität: AA 21-120

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human B3GAT1/CD57

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CD57 Antikörper (ABIN732308)

Kaneko, Sullivan, Dailey, Vale, Tajiri, Borlongan: "Kainic Acid-Induced Golgi Complex Fragmentation/Dispersal Shifts the Proteolysis of Reelin in Primary Rat Neuronal Cells: An In Vitro Model of Early Stage Epilepsy." in: Molecular neurobiology, (2015) (PubMed).

Salisbury, Lazard, Ubogu, Davis, Olmsted-Davis: "Transient brown adipocyte-like cells derive from peripheral nerve progenitors in response to bone morphogenetic protein 2." in: Stem cells translational medicine, Vol. 1, Issue 12, pp. 874-85, (2013) (PubMed).

Details zu CD57

Target: CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))

Andere Bezeichnung: B3GAT1/CD57

Hintergrund:

Synonyms: NK1, CD57, HNK1, LEU7, NK-1, GLCATP, GLCUATP, Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, Beta-1,3-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase, GlcUAT-P, B3GAT1

Background: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).

Gen-ID: 27087

UniProt: Q9P2W7

Pathways: Glycosaminoglycan Metabolic Process