LI Cadherin Antikörper (AA 242-418) (CF®647)

Produktnummer ABIN7656341

Der Maus Monoklonal Anti-LI Cadherin-Antikörper wurde für IHC, IHC (fp) und FACS validiert. Er ist geeignet, LI Cadherin in Proben von Human zu detektieren.

Kurzübersicht für LI Cadherin Antikörper (AA 242-418) (CF®647) (ABIN7656341)

Target: LI Cadherin

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LI Cadherin Antikörper ist konjugiert mit CF®647

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Flow Cytometry (FACS)

Klon: CDH17-2618

Produktdetails anti-LI Cadherin Antikörper (CF®647)

Bindungsspezifität: AA 242-418

Verwendungszweck: Cadherin 17 / LI Cadherin (Liver-Intestine Marker)(CDH17/2618), CF647 conjugate

Produktmerkmale: Cadherin 17, also known as LI cadherin (for liver-intestine cadherin), is a member of the cadherin family of calcium-dependent adhesion molecules. Cadherins mediate cell-cell interactions via hemophilic binding, and are critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. Cadherin 17 expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment (around aa 242-418) of human Cadherin 17 protein (CDH17)

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: MCF-7, HepG2 or HT29 cells. Stomach, Small Intestine, Colon or liver.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu LI Cadherin

Target: LI Cadherin

Andere Bezeichnung: Cadherin 17

Hintergrund:

Synonyms: Cadherin 17, Cadherin-17, CDH17, LI-cadherin, Liver-intestine cadherin, human peptide transporter 1 (HPT-1), Intestinal peptide-associated transporter HPT-1

Gene Symbol: CDH17

Tissue Expression: Intestine|Liver

Molekulargewicht: 120 kDa

Gen-ID: 1015

UniProt: Q12864