IL-10RA Antikörper (CF®488A)

Produktnummer ABIN7655655

Dieses Anti-IL-10RA-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von IL-10RA in FACS und Func. Geeignet für Maus.

Kurzübersicht für IL-10RA Antikörper (CF®488A) (ABIN7655655)

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL-10RA Antikörper ist konjugiert mit CF®488A

Applikation: Flow Cytometry (FACS), Functional Studies (Func)

Klon: 1B1-3a

Produktdetails anti-IL-10RA Antikörper (CF®488A)

Verwendungszweck: IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210)(1B1.3a), CF488A conjugate

Produktmerkmale: This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110 kDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Purified recombinant extracellular region of Mouse IL10RA

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: MPBMC . Spleen, Thymus, Lymph Node, Placenta, Lung or Liver.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu IL-10RA

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Andere Bezeichnung: IL-10R1

Hintergrund:

Synonyms: CD210 antigen, CDw210a, IBD28, IL10R alpha, IL-10R subunit 1, IL-10R1, IL10RA IL10RIL-10R subunit alpha, interleukin 10 receptor, alpha, interleukin-10 receptor alpha chain, Interleukin-10 receptor subunit 1

Tissue Expression: Lymphocytes|Monocytes/macrophages|NK cells

Molekulargewicht: 90-110 kDa

Gen-ID: 16154

UniProt: Q61727

Pathways: Growth Factor Binding