GATA3 Antikörper (AA 357-436) (CF®647)
Kurzübersicht für GATA3 Antikörper (AA 357-436) (CF®647) (ABIN7654314)
Target
Alle GATA3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 357-436
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Verwendungszweck
- GATA-3 (Breast and Urothelial Marker)(GATA3/2688), CF647 conjugate
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Produktmerkmale
- GATA-3 is a zinc finger transcription factor and plays an important role in promoting and directing cell proliferation, development, and differentiation in many tissues and cell types. GATA-3 expression is primarily seen in breast and urothelial carcinomas. 'Therefore, GATA3 antibody can be useful in the identification of unknown primary carcinoma when carcinomas of the breast or bladder are a possibility. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogen
- Recombinant fragment of human GATA3 protein (around aa 357-436)
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Isotyp
- IgG
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Applikationshinweise
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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Kommentare
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Positive Control: MCF-7 or T47D cells. Breast or Bladder Carcinoma.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % BSA, 0.05 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Protect from light
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Lagerung
- 4 °C
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Informationen zur Lagerung
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Haltbarkeit
- 24 months
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- GATA3 (GATA Binding Protein 3 (GATA3))
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Andere Bezeichnung
- GATA-3
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Hintergrund
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Synonyms: GATA3, GATA binding protein-3, GATA-binding factor 3, GATA3, HDR, HDRS, Transacting T-cell-specific transcription factor GATA-3
Gene Symbol: GATA3
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Molekulargewicht
- ~50 kDa
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Gen-ID
- 2625
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UniProt
- P23771
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Pathways
- Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
Target
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