FGA Antikörper

Produktnummer ABIN7654032

Dieses Anti-FGA-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von FGA in WB, IHC, IF, FACS und IHC (fp). Geeignet für Human.

Kurzübersicht für FGA Antikörper (ABIN7654032)

Target: FGA (Fibrinogen alpha Chain (FGA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FGA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: UC45

Produktdetails anti-FGA Antikörper

Verwendungszweck: Fibrinogen Alpha Chain(UC45)

Produktmerkmale: The plasma glycoprotein fibrinogen is synthesized in the liver and comprises three structurally different subunits: . Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i. e. the formation of fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (prothrombin and factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble fibrin clots and the promotion of platelet aggregation. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, which is the most abundant component of blood clots. The cleavage products of fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Human acute monoblastic leukemia cells.

Isotyp: IgM, kappa

Anwendungsinformationen

Applikationshinweise: ELISA: For coating, order antibody without BSA, Flow cytometry: 0.5-1 μg/million cells, Immunofluorescence: 0.5-1 μg/mL, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody

Kommentare:

Positive Control: Plasma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS, 0.05 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu FGA

Target: FGA (Fibrinogen alpha Chain (FGA))

Andere Bezeichnung: Fibrinogen Alpha Chain

Hintergrund:

Synonyms: Ac1873, Fba5e, FGA, Fib, Fib2, Fibrinogen alpha chain, Fibrinogen, A alpha polypeptide, Fibrinogen--alpha polypeptide chain, Fibrinopeptide A

Gene Symbol: FGA

Molekulargewicht: ~30 kDa

Gen-ID: 2243

UniProt: P02671