EBV EA p55,p50 Antikörper (CF®740)
Kurzübersicht für EBV EA p55,p50 Antikörper (CF®740) (ABIN7653709)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- p55,50 EBV-Early Antigen(1108-1), CF740 conjugate
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Produktmerkmale
- Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user
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Kommentare
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Positive Control: EBV-infected cells or tissues
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % rBSA, 0.05 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Protect from light
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Lagerung
- 4 °C
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Informationen zur Lagerung
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Haltbarkeit
- 24 months
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- EBV EA p55,p50 (Epstein-Barr Virus Early Antigen p55,p50 (EBV EA p55,p50))
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Andere Bezeichnung
- p55,50 EBV Early Antigen
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Substanzklasse
- Viral Protein
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Hintergrund
- EBNA1, EBV nuclear antigen 1, Epstein Barr nuclear antigen 1, Human Herpesvirus 4 (HHV4)
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Molekulargewicht
- 50/55 kDa doublet
Target
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