EZH2 Antikörper (CF®488A)

Produktnummer ABIN7653495

Dieses Anti-EZH2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von EZH2 in WB. Geeignet für Human.

Kurzübersicht für EZH2 Antikörper (CF®488A) (ABIN7653495)

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EZH2 Antikörper ist konjugiert mit CF®488A

Applikation: Western Blotting (WB)

Klon: EZH2-2536

Produktdetails anti-EZH2 Antikörper (CF®488A)

Verwendungszweck: EZH2 / KMT6(EZH2/2536), CF488A conjugate

Produktmerkmale: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human EZH2 protein

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Western blot 0.5-1.0 μg/mL, Optimal dilution for a specific application should be determined.

Kommentare:

Positive Control: MCF7, HeLa, U-2 OS or HEK-293 whole cell lysates. Human tonsil, testis or prostate tissue.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu EZH2

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Andere Bezeichnung: EZH2

Hintergrund:

Synonyms: Enhancer of zeste 2 polycomb repressive complex 2 subunit, Enhancer of zeste homolog 2 (EZH2), ENX1, Enx1h, EZH2b, Histone-lysine N-methyltransferase EZH2, KMT6, KMT6A, Lysine N-methyltransferase 6, WVS, WVS2

Gene Symbol: EZH2

Molekulargewicht: 81-102 kDa

Gen-ID: 2146

UniProt: Q15910

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation