Rekombinanter Elastin Antikörper (CF®647)

Produktnummer ABIN7653425

Der Kaninchen Monoklonal Anti-Elastin-Antikörper wurde für IHC und IHC (fp) validiert. Er ist geeignet, Elastin in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter Elastin Antikörper (CF®647) (ABIN7653425)

Target: Elastin (ELN)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Elastin Antikörper ist konjugiert mit CF®647

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: ELN-3131R

Produktdetails anti-Elastin Antikörper (CF®647)

Verwendungszweck: Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis)(ELN/3131R), CF647 conjugate

Produktmerkmale: Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human Elastin protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: A549 or U-2197 cells. Liver, Kidney, Lung or Intestine.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu Elastin

Target: Elastin (ELN)

Andere Bezeichnung: Elastin

Hintergrund:

Synonyms: Elastin, ELN, SVAS, Tropoelastin, WBS, WS

Gene Symbol: ELN

Molekulargewicht: 70 kDa

Gen-ID: 2006

UniProt: P15502

Pathways: Regulation of Actin Filament Polymerization