DBN1 Antikörper (AA 150-281) (CF®594)

Produktnummer ABIN7653290

Der Maus Monoklonal Anti-DBN1-Antikörper wurde für WB, IHC und IHC (fp) validiert. Er ist geeignet, DBN1 in Proben von Human zu detektieren.

Kurzübersicht für DBN1 Antikörper (AA 150-281) (CF®594) (ABIN7653290)

Target: DBN1 (Drebrin 1 (DBN1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DBN1 Antikörper ist konjugiert mit CF®594

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: DBN1-2879

Produktdetails anti-DBN1 Antikörper (CF®594)

Bindungsspezifität: AA 150-281

Verwendungszweck: Drebrin 1 (DBN1)(DBN1/2879), CF594 conjugate

Produktmerkmale: Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2), and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer's disease and Down syndrome. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment (aa 150-281) of human DBN1 protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu DBN1

Target: DBN1 (Drebrin 1 (DBN1))

Andere Bezeichnung: Drebrin 1

Hintergrund:

Synonyms: Developmentally regulated brain protein, Drebrin 1, Drebrin, Drebrin E, Drebrin E2, Drebrin1, DrebrinE

Gene Symbol: DBN1

Tissue Expression: Heart|Skeletal Muscle|Brain|Kidney|Neurons|Pancreas|Placenta

Molekulargewicht: 120 kDa

Gen-ID: 1627

UniProt: Q16643

Pathways: Maintenance of Protein Location