SIPA1 Antikörper (AA 351-450) (Biotin)

Produktnummer ABIN731905

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SIPA1 in ELISA, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SIPA1 Antikörper (AA 351-450) (Biotin) (ABIN731905)

Target: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIPA1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-SIPA1 Antikörper (Biotin)

Bindungsspezifität: AA 351-450

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SPA-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu SIPA1

Target: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Andere Bezeichnung: SPA-1/SIPA-1

Hintergrund:

Synonyms: GTPase activating protein Spa 1, GTPase-activating protein Spa-1, MGC102688, MGC17037, p130 SPA-1, p130 SPA1, Signal induced proliferation associated 1, Signal induced proliferation associated gene 1, Signal induced proliferation associated protein 1, signal-induced proliferation-associated gene 1, Signal-induced proliferation-associated protein 1, SIPA 1, Sipa-1, Sipa1, SIPA1_HUMAN, Spa1.

Background: The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.

Gen-ID: 6494

Pathways: Response to Water Deprivation