F13A1 Antikörper (AA 46-181) (CF®740)
Kurzübersicht für F13A1 Antikörper (AA 46-181) (CF®740) (ABIN7652469)
Target
Alle F13A1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 46-181
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Verwendungszweck
- Factor XIIIa (Coagulation Factor XIIIA Chain) (F13A1/1447), CF740 conjugate
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Produktmerkmale
- This antibody recognizes a protein of 83 kDa, which is identified as Factor XIIIa. It has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-factor XIIIa has been found to be useful in differentiating between dermatofibroma (almost all cases are positive), dermatofibrosarcoma protuberans (-/ ) and desmoplastic malignant melanoma (-). Anti-factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor, and meningioma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogen
- Recombinant fragment of human Factor XIIIa protein (aa46-181)
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Isotyp
- IgG2a
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Applikationshinweise
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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Kommentare
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Positive Control: 293T Cells. Placenta.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % rBSA, 0.05 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Protect from light
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Lagerung
- 4 °C
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Informationen zur Lagerung
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Haltbarkeit
- 24 months
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- F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))
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Andere Bezeichnung
- Factor-XIIIa
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Hintergrund
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Synonyms: Coagulation factor XIII A chain, Coagulation factor XIII A1 polypeptide, Coagulation factor XIIIa, F13A, F13a1, Factor XIIIA, Fibrin stabilizing factor, A subunit, Fibrinoligase, FSF, A subunit, Protein-glutamine gamma-glutamyltransferase A chain, TGase, Transglutaminase A chain, Transglutaminase. plasma
Gene Symbol: F13A1
Tissue Expression: Platelets|Uterus|Megakaryocytes|Monocytes/macrophages|Placenta|Prostate
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Molekulargewicht
- 83 kDa
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Gen-ID
- 2162
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UniProt
- P00488
Target
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