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CHD4 Antikörper (C-Term) (CF®405S)

Dieses Anti-CHD4-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CHD4 in WB, IHC, IF und IHC (fp). Geeignet für Human und Maus.
Produktnummer ABIN7652379

Kurzübersicht für CHD4 Antikörper (C-Term) (CF®405S) (ABIN7652379)

Target

Alle CHD4 Antikörper anzeigen
CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

Reaktivität

  • 51
  • 35
  • 8
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 36
  • 18
  • 1
Maus

Klonalität

  • 33
  • 22
Monoklonal

Konjugat

  • 37
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CHD4 Antikörper ist konjugiert mit CF®405S

Applikation

  • 38
  • 24
  • 20
  • 17
  • 11
  • 9
  • 6
  • 6
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon

3F2-4
  • Bindungsspezifität

    • 12
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Verwendungszweck

    CHD4(3F2/4), CF405S conjugate

    Produktmerkmale

    CHD4/Mi-2b is a component of the nucleosome remodeling and deacetylase (NuRD) complex which is a multi-subunit protein complex containing both histone deacetylase and nucleosome-dependent ATPase subunits. Current models predict that this complex function primarily in transcriptional repression. Accumulating evidence indicates that NuRD may regulate the transcription of specific genes by interacting with specific transcriptional factors. In addition, the NuRD complex may also participate in genome-wide transcriptional regulation through an association with histone tails. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogen

    Synthetic peptide (N- and C- terminal peptides were used for immunisation: 1. ASGLGSPSPCSAGSEEEDM & 2. CSRLANRAPEPPPQQVAQQQ) - which peptide the antibody recognises has not been tested.

    Isotyp

    IgG2a, kappa
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Kommentare

    Positive Control: HeLa whole cell lysate or human placenta tissue lysate. Human breast carcinoma.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % BSA, 0.05 % azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Protect from light

    Lagerung

    4 °C

    Informationen zur Lagerung

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Haltbarkeit

    24 months
  • Target

    CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

    Andere Bezeichnung

    CHD4

    Hintergrund

    Synonyms: ATP dependent helicase CHD4, Chromodomain helicase DNA binding protein 4, Mi 2 autoantigen 218 kDa protein, Mi 2b, Mi2 beta

    Gene Symbol: CHD4

    Molekulargewicht

    238 kDa

    Gen-ID

    1108

    UniProt

    Q14839
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