CD68 Antikörper (AA 150-221) (CF®647)
Kurzübersicht für CD68 Antikörper (AA 150-221) (CF®647) (ABIN7651877)
Target
Alle CD68 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 150-221
-
Verwendungszweck
- CD68 (Macrophage Marker)(C68/2709), CF647 conjugate
-
Produktmerkmale
- This antibody recognizes a glycoprotein of 110 kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
-
Immunogen
- Recombinant fragment of human CD68 protein (around aa 150-221)
-
Isotyp
- IgG2b, kappa
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Kommentare
-
Positive Control: Tonsil, lymph node, or spleen
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.1 mg/mL
-
Buffer
- PBS, 0.1 % BSA, 0.05 % azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Protect from light
-
Lagerung
- 4 °C
-
Informationen zur Lagerung
-
Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
-
Haltbarkeit
- 24 months
-
-
- CD68 (CD68 Molecule (CD68))
-
Andere Bezeichnung
- CD68
-
Hintergrund
-
Synonyms: GP110, LAMP4, Microsialin, Macrosialin, SCARD1, Scavenger Receptor Class D Member-1
Gene Symbol: CD68
Tissue Expression: Granulocytes|Monocytes/macrophages|Myeloid precursors
-
Molekulargewicht
- ~110 kDa
-
Gen-ID
- 968
-
UniProt
- P34810
Target
-