CD6 Antikörper

Produktnummer ABIN7651738

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD6 in FACS, IF und Func. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für CD6 Antikörper (ABIN7651738)

Target: CD6

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD6 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Klon: SPV-L14

Produktdetails anti-CD6 Antikörper

Verwendungszweck: CD6 (Negative Marker of T-regulatory Cells)(SPV-L14)

Produktmerkmale: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Immunogen: CD8 cytotoxic T-cell clone

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1-2 μg/mL. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user

Kommentare:

Positive Control: CCRF-CEM, Jurkat cells, Tonsil

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS, 0.05 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu CD6

Target: CD6

Andere Bezeichnung: CD6

Hintergrund:

Synonyms: T12, TP120

Gene Symbol: CD6

Tissue Expression: B-cells|T-cells

Molekulargewicht: 90-130 kDa

Gen-ID: 923

UniProt: P30203