Rekombinanter CA9 Antikörper (CF®405S)

Produktnummer ABIN7650481

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch CA9 in IHC und IHC (fp). Er zeigt eine Reaktivität gegenüber Human und Pferd.

Kurzübersicht für Rekombinanter CA9 Antikörper (CF®405S) (ABIN7650481)

Target: CA9 (Carbonic Anhydrase IX (CA9))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Pferd

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CA9 Antikörper ist konjugiert mit CF®405S

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: CA9-2993R

Produktdetails anti-CA9 Antikörper (CF®405S)

Verwendungszweck: Renal Cell Carcinoma (Carbonic Anhydrase IX) (CA9/2993R), CF405S conjugate

Produktmerkmale: Carbonic anhydrase IX (carbonic anhydrase 9) is one of several carbolic anhydrases that vary in tissue distribution and localization. Carbonic anhydrases catalyze the interconversion of carbon dioxide and water into carbonic acid and bicarbonate and are found in all mammalian tissues. Carbonic anhydrase IX is a transmembrane protein that is not expressed in most healthy tissues, but is expressed in most renal cell carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human CA9 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 0.5-1 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user

Kommentare:

Positive Control: Normal kidney or renal cell carcinoma

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu CA9

Target: CA9 (Carbonic Anhydrase IX (CA9))

Andere Bezeichnung: Carbonic Anhydrase IX

Hintergrund:

Synonyms: Carbonic anhydrase IX, Carbonic anhydrase 9, RCC-associated antigen G250, Carbonic dehydratase, CA-IX, Membrane antigen MN

Gene Symbol: CA9

Tissue Expression: Kidney

Molekulargewicht: 55 kDa

Gen-ID: 768

UniProt: Q16790