CALB1 Antikörper (AA 7-96) (CF®740)
Kurzübersicht für CALB1 Antikörper (AA 7-96) (CF®740) (ABIN7650291)
Target
Alle CALB1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 7-96
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Verwendungszweck
- Calbindin 1 (CALB1)(CALB1/3333), CF740 conjugate
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Produktmerkmale
- Calbindin 1, also known as calbindin D28K, is a member of a family of calcium binding proteins. This protein family also includes calmodulin, calbindin 2, S-100, and troponin C. Calbindin 1 is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, calbindin 1 acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, calbindin 1 modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, calbindin 1 has been implicated to play a role in apoptosis and microtubule function. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogen
- Recombinant fragment (around aa 7-96) of human CALB1 protein
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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Positive Control: 293T or HepG2 cells. Prostate, Lung, Pancreas, Kidney and Liver.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % rBSA, 0.05 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Protect from light
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Lagerung
- 4 °C
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Informationen zur Lagerung
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Haltbarkeit
- 24 months
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- CALB1 (Calbindin (CALB1))
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Andere Bezeichnung
- Calbindin 1
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Hintergrund
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Synonyms: Calbindin, Calbindin 1, Calbindin D28, Calbindin D28K, CALB1, Vitamin D dependent calcium binding protein
Gene Symbol: CALB1
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Molekulargewicht
- 52 kDa
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Gen-ID
- 793
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UniProt
- P05937
Target
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