ABO (Blood Group Antigen B) Antikörper (CF®405S)

Produktnummer ABIN7649063

Der Maus Monoklonal Anti--Antikörper wurde für IHC und IHC (fp) validiert. Er ist geeignet, in Proben von Human zu detektieren.

Kurzübersicht für ABO (Blood Group Antigen B) Antikörper (CF®405S) (ABIN7649063)

Target: ABO (Blood Group Antigen B)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: CF®405S

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: HEB-20

Produktdetails

Verwendungszweck: Blood Group Antigen B (CD173)(HEB-20), CF405S conjugate

Produktmerkmale: This antibody is applicable for staining ABO blood groups B and AB. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. Blood group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens. This antibody shows specific staining of erythrocytes and vascular epithelium of blood group B controls and no staining in group A controls. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Mixture of erythrocytes of group B and glyco protein fraction isolated from saliva of secretors with blood group B

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: KG1 cells. Human colorectal carcinoma tissues.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Antigendetails

Target: ABO (Blood Group Antigen B)

Andere Bezeichnung: Blood Group B

Hintergrund:

Synonyms: ABO Type B, Blood Group B

Gene Symbol: ABO

Molekulargewicht: Multiple

Gen-ID: 28

UniProt: P16442