APCDD1 Antikörper

Produktnummer ABIN731408

Produktdetails anti-APCDD1 Antikörper

Target: APCDD1 (Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APCDD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human APCDD1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu APCDD1

Target: APCDD1 (Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1))

Andere Bezeichnung: Apcdd1 (APCDD1 Produkte)

Synonyme: drapc1 antikoerper, xPgo antikoerper, APCDD1 antikoerper, Pgo1 antikoerper, cAPCDD1 antikoerper, B7323 antikoerper, DRAPC1 antikoerper, HHS antikoerper, HTS antikoerper, AB023957 antikoerper, AU041258 antikoerper, Drapc1 antikoerper, EIG180 antikoerper, adenomatosis polyposis coli down-regulated 1 antikoerper, APC down-regulated 1 antikoerper, adenomatosis polyposis coli down-regulated 1 L homeolog antikoerper, apcdd1 antikoerper, APCDD1 antikoerper, Apcdd1 antikoerper, apcdd1.L antikoerper

Hintergrund:

Synonyms: adenomatosio polyposis coli down-regulated 1, Adenomatosis polyposis coli down regulated 1, Adenomatosis polyposis coli down regulated 1 protein, APCDD 1, B7323, DRAPC1, FP7019, Protein APCDD1, APCD1_HUMAN.

Background: APCDD1 is a novel protein that has been shown to be a target of Wnt/beta catenin signaling pathway in cancer cell lines. APCDD1 is overexpressed in colorectal carcinogenesis and is deregulated in CTNNB1 mutated Wilms tumors.[FUNCTION] Probably plays a role in colorectal tumorigenesis. May be a developmental target gene of the Wnt/Beta-catenin pathway.[SUBCELLULAR LOCATION] Membrane, Single-pass type I membrane protein (Potential). [TISSUE SPECIFICITY] Abundantly expressed in heart, pancreas, prostate and ovary. Moderately expressed in lung, liver, kidney, spleen, thymus, colon and peripheral lymphocytes. [INDUCTION] Transcriptionally regulated by the CTNNB1/TF7L2complex.

Gen-ID: 147495