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BMP2 Antikörper (AA 283-365)

This anti-BMP2 antibody (ABIN730903) is a Rabbit Polyclonal antibody detecting BMP2 in WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro). Suitable for Human, Mouse, Rat, Rabbit, Sheep.
Produktnummer ABIN730903

Kurzübersicht für BMP2 Antikörper (AA 283-365) (ABIN730903)

Target

Alle BMP2 Antikörper anzeigen
BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Reaktivität

  • 113
  • 56
  • 55
  • 27
  • 18
  • 16
  • 15
  • 9
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Kaninchen, Schaf

Wirt

  • 142
  • 30
  • 9
  • 1
Kaninchen

Klonalität

  • 151
  • 31
Polyklonal

Konjugat

  • 95
  • 28
  • 13
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser BMP2 Antikörper ist unkonjugiert

Applikation

  • 158
  • 78
  • 54
  • 50
  • 49
  • 25
  • 25
  • 14
  • 10
  • 9
  • 9
  • 7
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 20
    • 15
    • 14
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 283-365

    Kreuzreaktivität

    Human, Maus, Kaninchen, Ratte, Schaf

    Homologie

    Dog,Cow,Horse,Chicken

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human BMP2

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Wu, Jiang, Feng, Jiang, Cheng: "Negative Pressure Therapy in the Regeneration of the Sciatic Nerve Using Vacuum - Assisted Closure in a Rabbit Model." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 1027-1033, (2018) (PubMed).

    Zhang, Wang, Shi, Wang, Lai, Yang, Chen, Yang: "Combination of simvastatin, calcium silicate/gypsum, and gelatin and bone regeneration in rabbit calvarial defects." in: Scientific reports, Vol. 6, pp. 23422, (2016) (PubMed).

    Zhou, Yin, Jiang, Niu, Wan, Chen, Shen: "CBX7 deficiency plays a positive role in dentin and alveolar bone development." in: Journal of molecular histology, Vol. 47, Issue 4, pp. 401-11, (2016) (PubMed).

    Sari, Rufaut, Jones, Sinclair: "Characterization of Ovine Dermal Papilla Cell Aggregation." in: International journal of trichology, Vol. 8, Issue 3, pp. 121-9, (2016) (PubMed).

    Naeem, Zhu, Di, Marmiroli, OShaughnessy: "AKT1-mediated Lamin A/C degradation is required for nuclear degradation and normal epidermal terminal differentiation." in: Cell death and differentiation, (2015) (PubMed).

    Wu, Zhou, Hu, Li: "Gene expression of osteogenic factors following gene therapy in mandibular lengthening." in: The Journal of craniofacial surgery, Vol. 26, Issue 2, pp. 378-81, (2015) (PubMed).

    Kishi, Fujihara, Kawaguchi, Yamada, Nakayama, Yamamoto, Fujihara, Hamada, Satomura, Masutani: "PARP Inhibitor PJ34 Suppresses Osteogenic Differentiation in Mouse Mesenchymal Stem Cells by Modulating BMP-2 Signaling Pathway." in: International journal of molecular sciences, Vol. 16, Issue 10, pp. 24820-38, (2015) (PubMed).

    Huang, Zou, Shi, Zhang, Pen, Zhang, Gao, Wang: "The effect of electroacupuncture on the extracellular matrix synthesis and degradation in a rabbit model of disc degeneration." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 731395, (2014) (PubMed).

    Wu, Chen, Mi, Chen, Wang, Gao: "Expression analysis of BMP2, BMP5, BMP10 in human colon tissues from Hirschsprung disease patients." in: International journal of clinical and experimental pathology, Vol. 7, Issue 2, pp. 529-36, (2014) (PubMed).

    Wang, Bi, Zhu, Wu, Wang: "Effects of the antihypertensive drug benidipine on osteoblast function in vitro." in: Experimental and therapeutic medicine, Vol. 7, Issue 3, pp. 649-653, (2014) (PubMed).

    Lescarbeau, Seib, Prewitz, Werner, Kaplan: "In vitro model of metastasis to bone marrow mediates prostate cancer castration resistant growth through paracrine and extracellular matrix factors." in: PLoS ONE, Vol. 7, Issue 8, pp. e40372, (2012) (PubMed).

  • Target

    BMP2 (Bone Morphogenetic Protein 2 (BMP2))

    Andere Bezeichnung

    BMP2

    Hintergrund

    Synonyms: BDA2, BMP2A, Bone morphogenetic protein 2, BMP-2, Bone morphogenetic protein 2A, BMP-2A, BMP2

    Background: BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis.

    Gen-ID

    650

    UniProt

    P12643

    Pathways

    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation
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