BMP2 Antikörper (AA 283-365)
Kurzübersicht für BMP2 Antikörper (AA 283-365) (ABIN730903)
Target
Alle BMP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
- 
    - 
                                            Bindungsspezifität
- AA 283-365
- 
                                            Kreuzreaktivität
- Human, Maus, Kaninchen, Ratte, Schaf
- 
                                            Homologie
- Dog,Cow,Horse,Chicken
- 
                                            Aufreinigung
- Purified by Protein A.
- 
                                            Immunogen
- KLH conjugated synthetic peptide derived from human BMP2
- 
                                            Isotyp
- IgG
 
- 
                                            
- 
    
- 
    - 
                                            Applikationshinweise
- 
                        WB 1:300-5000
 ELISA 1:500-1000
 IHC-P 1:200-400
 IHC-F 1:100-500
 IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
- 
                                            
- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 μg/μL
- 
                                            Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 
                                            Konservierungsmittel
- ProClin
- 
                                            Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            Lagerung
- 4 °C,-20 °C
- 
                                            Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 
                                            Haltbarkeit
- 12 months
 
- 
                                            
- 
    - 
                                            : "Negative Pressure Therapy in the Regeneration of the Sciatic Nerve Using Vacuum - Assisted Closure in a Rabbit Model."    in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 1027-1033, (2018)         (PubMed).        
 : "Combination of simvastatin, calcium silicate/gypsum, and gelatin and bone regeneration in rabbit calvarial defects." in: Scientific reports, Vol. 6, pp. 23422, (2016) (PubMed).
 : "CBX7 deficiency plays a positive role in dentin and alveolar bone development." in: Journal of molecular histology, Vol. 47, Issue 4, pp. 401-11, (2016) (PubMed).
 : "Characterization of Ovine Dermal Papilla Cell Aggregation." in: International journal of trichology, Vol. 8, Issue 3, pp. 121-9, (2016) (PubMed).
 : "AKT1-mediated Lamin A/C degradation is required for nuclear degradation and normal epidermal terminal differentiation." in: Cell death and differentiation, (2015) (PubMed).
 : "Gene expression of osteogenic factors following gene therapy in mandibular lengthening." in: The Journal of craniofacial surgery, Vol. 26, Issue 2, pp. 378-81, (2015) (PubMed).
 : "PARP Inhibitor PJ34 Suppresses Osteogenic Differentiation in Mouse Mesenchymal Stem Cells by Modulating BMP-2 Signaling Pathway." in: International journal of molecular sciences, Vol. 16, Issue 10, pp. 24820-38, (2015) (PubMed).
 : "The effect of electroacupuncture on the extracellular matrix synthesis and degradation in a rabbit model of disc degeneration." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 731395, (2014) (PubMed).
 : "Expression analysis of BMP2, BMP5, BMP10 in human colon tissues from Hirschsprung disease patients." in: International journal of clinical and experimental pathology, Vol. 7, Issue 2, pp. 529-36, (2014) (PubMed).
 : "Effects of the antihypertensive drug benidipine on osteoblast function in vitro." in: Experimental and therapeutic medicine, Vol. 7, Issue 3, pp. 649-653, (2014) (PubMed).
 : "In vitro model of metastasis to bone marrow mediates prostate cancer castration resistant growth through paracrine and extracellular matrix factors." in: PLoS ONE, Vol. 7, Issue 8, pp. e40372, (2012) (PubMed).
 
 
- 
                                            : "Negative Pressure Therapy in the Regeneration of the Sciatic Nerve Using Vacuum - Assisted Closure in a Rabbit Model."    in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 1027-1033, (2018)         (PubMed).        
- 
    - BMP2 (Bone Morphogenetic Protein 2 (BMP2))
- 
                                            Andere Bezeichnung
- BMP2
- 
                                            Hintergrund
- 
                        Synonyms: BDA2, BMP2A, Bone morphogenetic protein 2, BMP-2, Bone morphogenetic protein 2A, BMP-2A, BMP2 Background: BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis. 
- 
                                            Gen-ID
- 650
- 
                                            UniProt
- P12643
- 
                                            Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation
 Target
- 
                    
 
                                     
                                     
                                    