Dopamine d2 Receptor Antikörper (AA 201-300)

Produktnummer ABIN730858

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch Dopamine d2 Receptor in WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus und wurde in 8+ Publikationen erwähnt.

Kurzübersicht für Dopamine d2 Receptor Antikörper (AA 201-300) (ABIN730858)

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dopamine d2 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Dopamine d2 Receptor Antikörper

Bindungsspezifität: AA 201-300

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DRD2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Dopamine d2 Receptor Antikörper (ABIN730858)

Qian, Cai, Wang, Zhang, Zhao, Qian, Yang, Liu, Hasegawa: "Effect of Gingerol on Cisplatin-Induced Pica Analogous to Emesis Via Modulating Expressions of Dopamine 2 Receptor, Dopamine Transporter and Tyrosine Hydroxylase in the Vomiting Model of Rats." in: Yonago acta medica, Vol. 59, Issue 2, pp. 100-10, (2016) (PubMed).

Yano, Hide, Uekawa, Honda, Mikami, Kuratsu: "Mixed Pituitary Gangliocytoma and Prolactinoma Resistant to the Cabergoline Treatment." in: World neurosurgery, Vol. 95, pp. 620.e17-620.e22, (2016) (PubMed).

Zhang, Zhang, Zhang, Meng, Jia, Zhang, Bu, Zhu, Ma, Ye, Zhang, Ren, Sun, Tang: "Moderate swimming suppressed the growth and metastasis of the transplanted liver cancer in mice model: with reference to nervous system." in: Oncogene, Vol. 35, Issue 31, pp. 4122-31, (2016) (PubMed).

Mao, Yu, Hu, Hu: "Dopamine D2 receptor blocker thioridazine induces cell death in human uterine cervical carcinoma cell line SiHa." in: The journal of obstetrics and gynaecology research, Vol. 41, Issue 8, pp. 1240-5, (2015) (PubMed).

Salgado, López-Doval, Pereiro, Lafuente: "Perfluorooctane sulfonate (PFOS) exposure could modify the dopaminergic system in several limbic brain regions." in: Toxicology letters, Vol. 240, Issue 1, pp. 226-35, (2015) (PubMed).

Hu, Liu, Qiao: "Increased extracellular dopamine and 5-hydroxytryptamine levels contribute to enhanced subthalamic nucleus neural activity during exhausting exercise." in: Biology of sport, Vol. 32, Issue 3, pp. 187-92, (2015) (PubMed).

Xu, Wang, Chen, Chen, Li, Shao, Li, Lu, Zhou: "Dopamine D1 receptor activation induces dehydroepiandrosterone sulfotransferase (SULT2A1) in HepG2 cells." in: Acta pharmacologica Sinica, Vol. 35, Issue 7, pp. 889-98, (2014) (PubMed).

Details zu Dopamine d2 Receptor

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Andere Bezeichnung: DRD2

Hintergrund:

Synonyms: D2R, D2DR, D(2) dopamine receptor, Dopamine D2 receptor, DRD2

Background: Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.

Gen-ID: 1813

UniProt: P14416

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity