Endothelin 1 Antikörper (AA 53-73)

Produktnummer ABIN730258

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Endothelin 1 in WB, ELISA, IF (p), IHC (p), IF (cc) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human, Ratte, Schwein und Maus und wurde in 1 Publikation erwähnt.

Kurzübersicht für Endothelin 1 Antikörper (AA 53-73) (ABIN730258)

Target: Endothelin 1 (EDN1)

Reaktivität: Human, Ratte, Schwein, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Endothelin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Endothelin 1 Antikörper

Bindungsspezifität: AA 53-73

Kreuzreaktivität: Human, Maus, Schwein, Ratte

Homologie: Dog,Cow,Sheep,Horse,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human human Endothelin-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Endothelin 1 Antikörper (ABIN730258)

Hu, Yan, Wang, Meng, Pan: "Comparative analysis of preservation method and intermittent perfusion volume on the expression of endothelial and inflammatory markers by coronal artery and myocardium in porcine donor hearts." in: ASAIO journal (American Society for Artificial Internal Organs : 1992), Vol. 60, Issue 6, pp. 681-7, (2014) (PubMed).

Details zu Endothelin 1

Target: Endothelin 1 (EDN1)

Andere Bezeichnung: Endothelin-1

Hintergrund:

Synonyms: Endothelin-1, EDN 1, EDN1, EDN1 protein, Endothelin1, ET 1,ET1,

Background: Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver. Endothelin 1 is expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.

Gen-ID: 1906

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size