CBX5 Antikörper (pTyr43) (Biotin)

Produktnummer ABIN729960

Dieses Anti-CBX5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CBX5 in WB, ELISA, IHC (p) und IHC (fro). Geeignet für Others.

Kurzübersicht für CBX5 Antikörper (pTyr43) (Biotin) (ABIN729960)

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Reaktivität: Others

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBX5 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-CBX5 Antikörper (Biotin)

Bindungsspezifität: pTyr43

Kreuzreaktivität (Details): Fruit Fly

Homologie: Drosophila

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from Drosophila Melanogaster HP1 around the phosphorylation site of Tyr43

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:100-1000
IHC-P 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu CBX5

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Andere Bezeichnung: HP1

Hintergrund:

Synonyms: Heterochromatin protein 1, HP1, Non-histone chromosomal protein C1A9 antigen, CG8409

Background: HP1 alpha is a component of heterochromatin. It recognizes and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. HP1 alpha may interact with lamin B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, the chromo shadow domain. Both domains of HP1 are required for binding to native chromatin in vivo, but they contribute differentially to binding in euchromatin and heterochromatin.

Gen-ID: 34119