LAMR1CT (AA 201-295) Antikörper

Produktnummer ABIN729598

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch LAMR1CT in ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p) und WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für LAMR1CT (AA 201-295) Antikörper (ABIN729598)

Target: LAMR1CT

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Produktdetails

Bindungsspezifität: AA 201-295

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LAMR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen

Liu, Sun, Wu, Shi, Wang, Wang, Zhang, Zhang, Zhang: "MGr1-Ag/37LRP promotes growth and proliferation of gastric cancer in vitro and in vivo." in: Cancer gene therapy, Vol. 21, Issue 9, pp. 355-63, (2014) (PubMed).

Zhang, Wang, Xu, Dong, Liu, Zhou, Pang, Ma, Zhang, Pei, Zhang, Liu: "MGr1-Ag promotes invasion and bone metastasis of small-cell lung cancer in vitro and in vivo." in: Oncology reports, Vol. 29, Issue 6, pp. 2283-90, (2013) (PubMed).

Antigendetails

Target: LAMR1CT

Hintergrund:

Synonyms: SA, LBP, LRP, p4, 67LR, ICAS, lamR, 37LRP, LAMBR, LAMR1, LRP/LR, LBP/p4, NEM/1CHD4, 4S ribosomal protein SA, 37 kDa laminin receptor precursor, 37/67 kDa laminin receptor, 67 kDa laminin receptor, Colon carcinoma laminin-binding protein, Laminin receptor 1, Laminin-binding protein precursor p4, Multidrug resistance-associated protein MGr1-Ag, RPSA

Background: Required for the assembly and/or stability of the 4S ribosomal subunit. Required for the processing of the 2S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 4S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria.

Gen-ID: 3921

UniProt: P08865