Granulin Antikörper (AA 451-550)
Kurzübersicht für Granulin Antikörper (AA 451-550) (ABIN728668)
Target
Alle Granulin (GRN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 451-550
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Spezifität
- This antibody is specific for Granulin-6
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Kreuzreaktivität
- Human
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Homologie
- Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit,Guinea Pig
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Granulin
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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: "The molecular basis for development of proinflammatory autoantibodies to progranulin." in: Journal of autoimmunity, Vol. 61, pp. 17-28, (2015) (PubMed).
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: "The molecular basis for development of proinflammatory autoantibodies to progranulin." in: Journal of autoimmunity, Vol. 61, pp. 17-28, (2015) (PubMed).
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- Granulin (GRN)
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Andere Bezeichnung
- Granulin
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Hintergrund
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Synonyms: GEP, GP88, PEPI, PGRN, CLN11, PCDGF, Granulins, Proepithelin, GRN
Background: Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth.
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Gen-ID
- 2896
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UniProt
- P28799
Target
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