CGRP Antikörper (AA 65-130)

Produktnummer ABIN728218

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CGRP in ELISA, WB, IHC (p), IF (cc), IF (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human und Ratte und wurde in 7+ Publikationen erwähnt.

Kurzübersicht für CGRP Antikörper (AA 65-130) (ABIN728218)

Target: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CGRP Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-CGRP Antikörper

Bindungsspezifität: AA 65-130

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Cow,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CALCA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CGRP Antikörper (ABIN728218)

He, Xiong, Liu, He, Feng, Shang, Xia, Wang, Qiu, Luo, Liu, Wang: "MicroRNA-127 targeting of mitoNEET inhibits neurite outgrowth, induces cell apoptosis and contributes to physiological dysfunction after spinal cord transection." in: Scientific reports, Vol. 6, pp. 35205, (2016) (PubMed).

Liu, Peng, Long, Li, Ke, Fang: "Mutual effect between neuropeptides and inflammatory cytokines in neurogenic SMSCs of human temporomandibular joint." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 4, pp. 602-7, (2014) (PubMed).

Wang, Sun, Tang, Guo, Zhou, Chen, Shen: "Basic fibroblast growth factor attenuates the degeneration of injured spinal cord motor endplates." in: Neural regeneration research, Vol. 8, Issue 24, pp. 2213-24, (2014) (PubMed).

Tu, Li, Peng, Hu, Liu, Kong, Liu, Gao, Xu, Xu, Qiu, Fan, Zhu, Yu, Zheng, Wu, Peng, Song, Wu, Liang: "P2X(7) inhibition in stellate ganglia prevents the increased sympathoexcitatory reflex via sensory-sympathetic coupling induced by myocardial ischemic injury." in: Brain research bulletin, Vol. 96, pp. 71-85, (2013) (PubMed).

Liu, Li, Peng, Tu, Kong, Liu, Gao, Xu, Qiu, Fan, Zhu, Yu, Zheng, Wu, Peng, Song, Wu, Li, Liang: "Sensory-sympathetic coupling in superior cervical ganglia after myocardial ischemic injury facilitates sympathoexcitatory action via P2X7 receptor." in: Purinergic signalling, Vol. 9, Issue 3, pp. 463-79, (2013) (PubMed).

Li, Zhang, Zhang, Ma: "The protective effect of genistein postconditioning on hypoxia/reoxygenation-induced injury in human gastric epithelial cells." in: Acta pharmacologica Sinica, Vol. 30, Issue 5, pp. 576-81, (2009) (PubMed).

Details zu CGRP

Target: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Andere Bezeichnung: CGRP

Hintergrund:

Synonyms: CAL6, CGRP, Cal1, Calc, RATCAL6, calcitonin, Calcitonin gene-related peptide 1, Alpha-type CGRP, Calcitonin gene-related peptide I, CGRP-I, Calca

Background: CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role.

Gen-ID: 24241

UniProt: P06881

Pathways: Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour