CGRP Antikörper (AA 65-130)

Produktnummer ABIN728218

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CGRP in ELISA, WB, IHC (p), IF (cc), IF (p) und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human und Ratte. Es wurde in 7+ Publikationen zitiert.

Kurzübersicht für CGRP Antikörper (AA 65-130) (ABIN728218)

Target: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CGRP Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-CGRP Antikörper

Bindungsspezifität: AA 65-130

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Cow,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CALCA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CGRP Antikörper (ABIN728218)

He, Xiong, Liu, He, Feng, Shang, Xia, Wang, Qiu, Luo, Liu, Wang: "MicroRNA-127 targeting of mitoNEET inhibits neurite outgrowth, induces cell apoptosis and contributes to physiological dysfunction after spinal cord transection." in: Scientific reports, Vol. 6, pp. 35205, (2016) (PubMed).

Liu, Peng, Long, Li, Ke, Fang: "Mutual effect between neuropeptides and inflammatory cytokines in neurogenic SMSCs of human temporomandibular joint." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 4, pp. 602-7, (2014) (PubMed).

Wang, Sun, Tang, Guo, Zhou, Chen, Shen: "Basic fibroblast growth factor attenuates the degeneration of injured spinal cord motor endplates." in: Neural regeneration research, Vol. 8, Issue 24, pp. 2213-24, (2014) (PubMed).

Tu, Li, Peng, Hu, Liu, Kong, Liu, Gao, Xu, Xu, Qiu, Fan, Zhu, Yu, Zheng, Wu, Peng, Song, Wu, Liang: "P2X(7) inhibition in stellate ganglia prevents the increased sympathoexcitatory reflex via sensory-sympathetic coupling induced by myocardial ischemic injury." in: Brain research bulletin, Vol. 96, pp. 71-85, (2013) (PubMed).

Liu, Li, Peng, Tu, Kong, Liu, Gao, Xu, Qiu, Fan, Zhu, Yu, Zheng, Wu, Peng, Song, Wu, Li, Liang: "Sensory-sympathetic coupling in superior cervical ganglia after myocardial ischemic injury facilitates sympathoexcitatory action via P2X7 receptor." in: Purinergic signalling, Vol. 9, Issue 3, pp. 463-79, (2013) (PubMed).

Li, Zhang, Zhang, Ma: "The protective effect of genistein postconditioning on hypoxia/reoxygenation-induced injury in human gastric epithelial cells." in: Acta pharmacologica Sinica, Vol. 30, Issue 5, pp. 576-81, (2009) (PubMed).

Details zu CGRP

Target: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Andere Bezeichnung: CGRP

Hintergrund:

Synonyms: CAL6, CGRP, Cal1, Calc, RATCAL6, calcitonin, Calcitonin gene-related peptide 1, Alpha-type CGRP, Calcitonin gene-related peptide I, CGRP-I, Calca

Background: CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role.

Gen-ID: 24241

UniProt: P06881

Pathways: Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour