Der Kaninchen Monoklonal anti-SARS-CoV-2 Nucleocapsid Antikörper wird verwendet zum Nachweis von SARS-CoV-2 Nucleocapsid in Proben von SARS Coronavirus-2 (SARS-CoV-2). Er wurde validiert für ELISA.
SARS-CoV-2 N
Reaktivität: SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV)
ELISA, IF, Neut
Wirt: Human
Monoclonal
CR3018 (03-018)
unconjugated
Recombinant Antibody
Applikationshinweise
ELISA 1:5000-10000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Lagerung
-20 °C,-80 °C
Informationen zur Lagerung
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Haltbarkeit
12 months
Target
SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
Andere Bezeichnung
SARS-CoV-2 N
Hintergrund
Coronavirus contain most of nucleocapsid protein. Coronavirus nucleoproteins (N proteins) localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. The nucleolus is the site of ribosome biogenesis and sequesters cell cycle regulatory complexes. Two of the major components of the nucleolus are fibrillarin and nucleolin. These proteins are involved in nucleolar assembly and ribosome biogenesis and act as chaperones for the import of proteins into the nucleolus. Regarding of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is a tool for diagnostic.