Der Biotin-konjugierte Kaninchen Monoklonal anti-IL17RA Antikörper (Klon DM126) (ABIN7608279) detektiert spezifisch IL17RA in ELISA und FACS.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Please see Certificate of Analysis for specific instructions of reconstitution.
Buffer
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Lagerung
-20 °C,-80 °C
Informationen zur Lagerung
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Haltbarkeit
12 months
Target
IL17RA
(Interleukin 17 Receptor A (IL17RA))
Andere Bezeichnung
IL17RA
Hintergrund
Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.