SMURF2 Antikörper

Produktnummer ABIN7606330

Der Kaninchen Monoklonal Anti-SMURF2-Antikörper wurde für WB validiert. Er ist geeignet, SMURF2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SMURF2 Antikörper (ABIN7606330)

Target: SMURF2 (SMAD Specific E3 Ubiquitin Protein Ligase 2 (SMURF2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser SMURF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: AECF-19

Produktdetails anti-SMURF2 Antikörper

Verwendungszweck: Anti-SMURF 2 Rabbit Monoclonal Antibody

Produktmerkmale: Anti-SMURF 2 Rabbit Monoclonal Antibody (ABIN7606330). Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human SMURF 2 E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then ly transfers the ubiquitin to targeted substrates. Interacts with SMAD1 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Konzentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Details zu SMURF2

Target: SMURF2 (SMAD Specific E3 Ubiquitin Protein Ligase 2 (SMURF2))

Andere Bezeichnung: SMURF2

Hintergrund:

Synonyms: Neurogenic locus notch homolog protein 4,Notch 4,hNotch4,Notch 4 extracellular truncation,Notch 4 intracellular domain,NOTCH4,INT3,

Tissue Specificity: Highly expressed in the heart, moderately in the lung and placenta and at low levels in the liver, skeletal muscle, kidney, pancreas, spleen, lymph node, thymus, bone marrow and fetal liver. No expression was seen in adult brain or peripheral blood leukocytes.

Molekulargewicht: 41 kDa