SIRT2 Antikörper

Produktnummer ABIN7606297

Der Kaninchen Monoklonal Anti-SIRT2-Antikörper wurde für WB validiert. Er ist geeignet, SIRT2 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für SIRT2 Antikörper (ABIN7606297)

Target: SIRT2 (Sirtuin 2 (SIRT2))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser SIRT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: HCA-19

Produktdetails anti-SIRT2 Antikörper

Verwendungszweck: Anti-SIRT2/Sirtuin 2 Rabbit Monoclonal Antibody

Produktmerkmale: Anti-SIRT2/Sirtuin 2 Rabbit Monoclonal Antibody (ABIN7606297). Tested in WB application. This antibody reacts with Human, Rat.

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human SIRT2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Konzentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Details zu SIRT2

Target: SIRT2 (Sirtuin 2 (SIRT2))

Andere Bezeichnung: SIRT2

Hintergrund:

Synonyms: NAD-dependent protein deacetylase sirtuin-2,3.5.1.-,Regulatory protein SIR2 homolog 2,SIR2-like protein 2,SIRT2,SIR2L, SIR2L2,

Tissue Specificity: Isoform 1 is expressed in heart, liver and skeletal muscle, weakly expressed in the cortex. Isoform 2 is strongly expressed in the cortex, weakly expressed in heart and liver. Weakly expressed in several malignancies including breast, liver, brain, kidney and prostate cancers compared to normal tissues. Weakly expressed in glioma cell lines compared to normal brain tissues (at protein level). Widely expressed. Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung. Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network. .

Molekulargewicht: 160-180 kDa