PTTG1 Antikörper
Kurzübersicht für PTTG1 Antikörper (ABIN7606263)
Target
Alle PTTG1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Securin Monoclonal Antibody
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Produktmerkmale
- Anti-Securin Monoclonal Antibody. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.
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Aufreinigung
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human Securin Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000IHC 1:50-200ICC/IF 1:50-200IP 1:30FC 1:50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))
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Andere Bezeichnung
- PTTG1
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Hintergrund
- PTTG1 regulator of sister chromatid separation, securin
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Molekulargewicht
- 26 kDa
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Gen-ID
- 9232
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UniProt
- O95997
Target
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