Dihydrofolate Reductase Antikörper

Produktnummer ABIN7604645

Dieses Anti-Dihydrofolate Reductase-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von Dihydrofolate Reductase in WB, IHC, IF und ICC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Dihydrofolate Reductase Antikörper (ABIN7604645)

Target: Dihydrofolate Reductase (DHFR)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Dihydrofolate Reductase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: ACBE-4

Produktdetails anti-Dihydrofolate Reductase Antikörper

Verwendungszweck: Anti-DHFR Monoclonal Antibody

Produktmerkmale: Anti-DHFR Monoclonal Antibody (ABIN7604645). Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human DHFR Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:5000
IHC 1:50-1:200
ICC/IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Konzentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Details zu Dihydrofolate Reductase

Target: Dihydrofolate Reductase (DHFR)

Andere Bezeichnung: DHFR

Hintergrund:

Synonyms: Scavenger receptor cysteine-rich type 1 protein M130,Hemoglobin scavenger receptor,CD163,Soluble CD163,sCD163,CD163,M130,

Tissue Specificity: Expressed in monocytes and mature macrophages such as Kupffer cells in the liver, red pulp macrophages in the spleen, cortical macrophages in the thymus, resident bone marrow macrophages and meningeal macrophages of the central nervous system. Expressed also in blood. Isoform 1 is the lowest abundant in the blood. Isoform 2 is the lowest abundant in the liver and the spleen. Isoform 3 is the predominant isoform detected in the blood. .

Molekulargewicht: 180 kDa

UniProt: P00374

Pathways: Mitotic G1-G1/S Phases